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Image Search Results


Structure, function, and regulatory mechanisms of CRL5, along with the upstream and downstream signaling pathways of CUL5 in different tumors.

Journal: Frontiers in Medicine

Article Title: CUL5-mediated ubiquitination in cancer cell therapy: context-dependent roles, molecular networks, and emerging therapeutic avenues

doi: 10.3389/fmed.2026.1775447

Figure Lengend Snippet: Structure, function, and regulatory mechanisms of CRL5, along with the upstream and downstream signaling pathways of CUL5 in different tumors.

Article Snippet: Similarly, CUL5 ubiquitinates AQP2, further influencing vascular dynamics ( , ), suggesting broader roles in fluid homeostasis during vascular development.

Techniques: Protein-Protein interactions

Regulation and downstream effects of CUL5 in CAR-T cells.

Journal: Frontiers in Medicine

Article Title: CUL5-mediated ubiquitination in cancer cell therapy: context-dependent roles, molecular networks, and emerging therapeutic avenues

doi: 10.3389/fmed.2026.1775447

Figure Lengend Snippet: Regulation and downstream effects of CUL5 in CAR-T cells.

Article Snippet: Similarly, CUL5 ubiquitinates AQP2, further influencing vascular dynamics ( , ), suggesting broader roles in fluid homeostasis during vascular development.

Techniques:

Connexin 43 (Cx43) expression in different cellular populations of renal tissue sections from control (C) and diabetic patients (DM). Representative photomicrographs show Cx43 (Cx43, green) expression in the kidneys of control and diabetic groups co-localized with ( a ) aquaporin 2 (AQP2, red), a marker for collecting duct epithelium; ( b ) synaptopodin, a marker for podocytes (synaptopodin, red) and ( c ) PDGFRB, a marker for pericytes and mesangial cells (PDGFRB, red). g—glomerulus; arrowheads indicate positive Cx43 staining. Nuclei are stained blue. Scale bar = 50 µm (refers to all).

Journal: International Journal of Molecular Sciences

Article Title: Connexin 43 and Pannexin 1 in Renal Cell Populations in Diabetic Kidney Disease

doi: 10.3390/ijms27052152

Figure Lengend Snippet: Connexin 43 (Cx43) expression in different cellular populations of renal tissue sections from control (C) and diabetic patients (DM). Representative photomicrographs show Cx43 (Cx43, green) expression in the kidneys of control and diabetic groups co-localized with ( a ) aquaporin 2 (AQP2, red), a marker for collecting duct epithelium; ( b ) synaptopodin, a marker for podocytes (synaptopodin, red) and ( c ) PDGFRB, a marker for pericytes and mesangial cells (PDGFRB, red). g—glomerulus; arrowheads indicate positive Cx43 staining. Nuclei are stained blue. Scale bar = 50 µm (refers to all).

Article Snippet: , Anti-Aquaporin 2/AQP2 (E-2) , sc-515770 , Mouse , 1:50 , Santa Cruz Biotechnology Inc., Santa Cruz, CA, USA.

Techniques: Expressing, Control, Marker, Staining

Pannexin 1 (PANX1) expression in different cellular populations of renal tissue sections from control (C) and diabetic (DM) patients. Representative photomicrographs show PANX1 (PANX1, green) expression in the kidneys of control and diabetic groups co-localized with ( a ) aquaporin 2 (AQP2, red), a marker for collecting duct epithelium; ( b ) nephrin (nephrin, red) a marker for podocytes. Arrowheads indicate positive PANX1 staining. Nuclei are stained blue. Scale bar = 50 µm (refers to all). g—glomerulus.

Journal: International Journal of Molecular Sciences

Article Title: Connexin 43 and Pannexin 1 in Renal Cell Populations in Diabetic Kidney Disease

doi: 10.3390/ijms27052152

Figure Lengend Snippet: Pannexin 1 (PANX1) expression in different cellular populations of renal tissue sections from control (C) and diabetic (DM) patients. Representative photomicrographs show PANX1 (PANX1, green) expression in the kidneys of control and diabetic groups co-localized with ( a ) aquaporin 2 (AQP2, red), a marker for collecting duct epithelium; ( b ) nephrin (nephrin, red) a marker for podocytes. Arrowheads indicate positive PANX1 staining. Nuclei are stained blue. Scale bar = 50 µm (refers to all). g—glomerulus.

Article Snippet: , Anti-Aquaporin 2/AQP2 (E-2) , sc-515770 , Mouse , 1:50 , Santa Cruz Biotechnology Inc., Santa Cruz, CA, USA.

Techniques: Expressing, Control, Marker, Staining